TB-500

The Thymosin Beta-4

Comprehensive evidence-based information on tissue and gut repair

Primary Benefit

Systemic Healing Tissue & Gut Repair Recovery

Administration

Injectable, Capsules

Status

Research Compound

Clinical Insights

Evidence-based analysis from Dr. Jobby John, PharmD, FACA

Provider Access

What is TB-500?

TB-500, whose name stands for 'Thymosin Beta-4,' is a synthetic peptide made of 15 amino acids. It is a partial sequence of a protein found naturally in human gastric juice.

A Natural Blueprint

It's a synthetic peptide, but it's based on a protective protein your own body makes, specifically in your gastric juice.

The Repair Signal

Its main job is to kickstart and accelerate healing. Imagine it as the foreman on a construction site, telling the body's repair crews exactly where to go and what to do.

Research and Potential Benefits

Perhaps the most famous application of TB-500 is its effect on connective tissues like tendons, ligaments, and muscle.

  • Accelerates Healing: Studies show it can significantly speed up the repair of tendons, ligaments, and skin.
  • Promotes Angiogenesis: It encourages the formation of new blood vessels, which is critical for bringing nutrients to an injured area.
  • Reduces Inflammation: Acts as a potent anti-inflammatory agent at the site of injury.

Originating from gastric juice, TB-500 has a natural affinity for the gastrointestinal tract.

  • Heals Ulcers: Research suggests it can protect and heal the stomach lining from ulcer damage.
  • Soothes IBD: May reduce inflammation associated with conditions like Crohn's disease and ulcerative colitis.
  • 'Seals' Leaky Gut: Appears to maintain and restore the integrity of the gut barrier.

TB-500 is a research compound. As a synthetic version of a naturally occurring peptide, it is generally considered to have a high safety profile.

  • ! Localized Action: Unlike some peptides, TB-500 tends to have a more localized effect when injected near an injury site.
  • ! Few Reported Side Effects: In research, it is noted for its lack of significant adverse side effects.
  • ! Professional Guidance Recommended: Consultation with a knowledgeable healthcare provider is important to determine appropriate use and dosing.

References & Citations

  1. Seiwerth, S., et al. (2018). BPC 157 and Standard Angiogenic Growth Factors. Source.
  2. Chang, C. H., et al. (2011). The promoting effect of pentadecapeptide BPC 157 on tendon healing... Source.
Dr. Jobby John

Ask Dr. John About TB-500

Get personalized clinical insights from Dr. Jobby John, PharmD, FACA. Ask specific questions about TB-500 and receive evidence-based answers from his extensive clinical experience.

Ask about dosing, administration routes, healing protocols, safety considerations, or clinical applications

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